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Nanomechanics and intermolecular forces of amyloid revealed by four-dimensional electron microscopy
The amyloid state of polypeptides is a stable, highly organized structural form consisting of laterally associated β-sheet protofilaments that may be adopted as an alternative to the functional, native state. Identifying the balance of forces stabilizing amyloid is fundamental to understanding the w...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4371943/ https://ncbi.nlm.nih.gov/pubmed/25733888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1502214112 |
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