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Rationally designed fluorogenic protease reporter visualizes spatiotemporal dynamics of apoptosis in vivo
Fluorescence resonance energy transfer-based reporters have been widely used in imaging cell signaling; however, their in vivo application has been handicapped because of poor signal. Although fluorogenic reporters overcome this problem, no such reporter of proteases has been demonstrated for in viv...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4371907/ https://ncbi.nlm.nih.gov/pubmed/25733847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1502857112 |
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