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Structure‐guided design of a reversible fluorogenic reporter of protein‐protein interactions

A reversible green fluorogenic protein‐fragment complementation assay was developed based on the crystal structure of UnaG, a recently discovered fluorescent protein. In living mammalian cells, the nonfluorescent fragments complemented and rapidly became fluorescent upon rapamycin‐induced FKBP and F...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: To, Tsz‐Leung, Zhang, Qiang, Shu, Xiaokun
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815423/
https://ncbi.nlm.nih.gov/pubmed/26690964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2866
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