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Precision Optogenetic Tool for Selective Single- and Multiple-Cell Ablation in a Live Animal Model System

Cell ablation is a strategy to study cell lineage and function during development. Optogenetic methods are an important cell-ablation approach, and we have previously developed a mini singlet oxygen generator (miniSOG) tool that works in the living Caenorhabditis elegans. Here, we use directed evolu...

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Bibliographic Details
Published in:Cell Chem Biol
Main Authors: Makhijani, Kalpana, To, Tsz-Leung, Ruiz-González, Rubén, Lafaye, Céline, Royant, Antoine, Shu, Xiaokun
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5304914/
https://ncbi.nlm.nih.gov/pubmed/28065655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2016.12.010
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