Serine palmitoyltransferase (SPT) deficient mice absorb less cholesterol()

Serine palmitoyltransferase (SPT) is the key enzyme for the biosynthesis of sphingolipids. It has been reported that oral administration of myriocin (an SPT inhibitor) decreases plasma sphingomyelin (SM) and cholesterol levels, and reduces atherosclerosis in apoE knockout (KO) mice. We studied chole...

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Publicat a:Biochim Biophys Acta
Autors principals: Li, Zhiqiang, Park, Tae-Sik, Li, Yan, Pan, Xiaoyue, Iqbal, Jahangir, Lu, David, Tang, Weiqing, Yu, Liqing, Goldberg, Ira J., Hussain, M. Mahmood, Jiang, Xian-Cheng
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4371774/
https://ncbi.nlm.nih.gov/pubmed/19416652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2009.01.010
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