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Impaired Cholesterol Metabolism and Enhanced Atherosclerosis in Clock Mutant Mice
BACKGROUND: Clock is a key transcription factor that positively controls circadian regulation. However, its role in plasma cholesterol homeostasis and atherosclerosis has not been studied. METHODS AND RESULTS: We show for the first time that dominant-negative Clock mutant protein (Clock(Δ19/Δ19)) en...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3897228/ https://ncbi.nlm.nih.gov/pubmed/24014832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.113.002885 |
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