Serine palmitoyltransferase (SPT) deficient mice absorb less cholesterol()

Serine palmitoyltransferase (SPT) is the key enzyme for the biosynthesis of sphingolipids. It has been reported that oral administration of myriocin (an SPT inhibitor) decreases plasma sphingomyelin (SM) and cholesterol levels, and reduces atherosclerosis in apoE knockout (KO) mice. We studied chole...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Li, Zhiqiang, Park, Tae-Sik, Li, Yan, Pan, Xiaoyue, Iqbal, Jahangir, Lu, David, Tang, Weiqing, Yu, Liqing, Goldberg, Ira J., Hussain, M. Mahmood, Jiang, Xian-Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4371774/
https://ncbi.nlm.nih.gov/pubmed/19416652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2009.01.010
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