Serine palmitoyltransferase (SPT) deficient mice absorb less cholesterol()

Serine palmitoyltransferase (SPT) is the key enzyme for the biosynthesis of sphingolipids. It has been reported that oral administration of myriocin (an SPT inhibitor) decreases plasma sphingomyelin (SM) and cholesterol levels, and reduces atherosclerosis in apoE knockout (KO) mice. We studied chole...

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Bibliografiset tiedot
Julkaisussa:Biochim Biophys Acta
Päätekijät: Li, Zhiqiang, Park, Tae-Sik, Li, Yan, Pan, Xiaoyue, Iqbal, Jahangir, Lu, David, Tang, Weiqing, Yu, Liqing, Goldberg, Ira J., Hussain, M. Mahmood, Jiang, Xian-Cheng
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4371774/
https://ncbi.nlm.nih.gov/pubmed/19416652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2009.01.010
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