Serine palmitoyltransferase (SPT) deficient mice absorb less cholesterol()

Serine palmitoyltransferase (SPT) is the key enzyme for the biosynthesis of sphingolipids. It has been reported that oral administration of myriocin (an SPT inhibitor) decreases plasma sphingomyelin (SM) and cholesterol levels, and reduces atherosclerosis in apoE knockout (KO) mice. We studied chole...

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Vydáno v:Biochim Biophys Acta
Hlavní autoři: Li, Zhiqiang, Park, Tae-Sik, Li, Yan, Pan, Xiaoyue, Iqbal, Jahangir, Lu, David, Tang, Weiqing, Yu, Liqing, Goldberg, Ira J., Hussain, M. Mahmood, Jiang, Xian-Cheng
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4371774/
https://ncbi.nlm.nih.gov/pubmed/19416652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2009.01.010
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