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Single-Molecule Imaging Reveals that Small Amyloid-β(1–42) Oligomers Interact with the Cellular Prion Protein (PrP(C))
Oligomers of the amyloid-β peptide (Aβ) play a central role in the pathogenesis of Alzheimer’s disease and have been suggested to induce neurotoxicity by binding to a plethora of cell-surface receptors. However, the heterogeneous mixtures of oligomers of varying sizes and conformations formed by Aβ4...
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| Опубликовано в: : | Chembiochem |
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| Главные авторы: | , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
WILEY-VCH Verlag
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4371635/ https://ncbi.nlm.nih.gov/pubmed/25294384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201402377 |
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