The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family

The genus Enterovirus of the family Picornaviridae contains many important human pathogens (e.g., poliovirus, coxsackievirus, rhinovirus, and enterovirus 71) for which no antiviral drugs are available. The viral RNA-dependent RNA polymerase is an attractive target for antiviral therapy. Nucleoside-b...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:PLoS Pathog
Κύριοι συγγραφείς: van der Linden, Lonneke, Vives-Adrián, Laia, Selisko, Barbara, Ferrer-Orta, Cristina, Liu, Xinran, Lanke, Kjerstin, Ulferts, Rachel, De Palma, Armando M., Tanchis, Federica, Goris, Nesya, Lefebvre, David, De Clercq, Kris, Leyssen, Pieter, Lacroix, Céline, Pürstinger, Gerhard, Coutard, Bruno, Canard, Bruno, Boehr, David D., Arnold, Jamie J., Cameron, Craig E., Verdaguer, Nuria, Neyts, Johan, van Kuppeveld, Frank J. M.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2015
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370873/
https://ncbi.nlm.nih.gov/pubmed/25799064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004733
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