The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family

The genus Enterovirus of the family Picornaviridae contains many important human pathogens (e.g., poliovirus, coxsackievirus, rhinovirus, and enterovirus 71) for which no antiviral drugs are available. The viral RNA-dependent RNA polymerase is an attractive target for antiviral therapy. Nucleoside-b...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:PLoS Pathog
मुख्य लेखकों: van der Linden, Lonneke, Vives-Adrián, Laia, Selisko, Barbara, Ferrer-Orta, Cristina, Liu, Xinran, Lanke, Kjerstin, Ulferts, Rachel, De Palma, Armando M., Tanchis, Federica, Goris, Nesya, Lefebvre, David, De Clercq, Kris, Leyssen, Pieter, Lacroix, Céline, Pürstinger, Gerhard, Coutard, Bruno, Canard, Bruno, Boehr, David D., Arnold, Jamie J., Cameron, Craig E., Verdaguer, Nuria, Neyts, Johan, van Kuppeveld, Frank J. M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2015
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370873/
https://ncbi.nlm.nih.gov/pubmed/25799064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004733
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