Overexpression of SIRT1 in Rat Skeletal Muscle Does Not Alter Glucose Induced Insulin Resistance

SIRT1 is a NAD(+)-dependent deacetylase thought to regulate cellular metabolic pathways in response to alterations in nutrient flux. In the current study we investigated whether acute changes in SIRT1 expression affect markers of muscle mitochondrial content and also determined whether SIRT1 influen...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Brandon, Amanda E., Tid-Ang, Jennifer, Wright, Lauren E., Stuart, Ella, Suryana, Eurwin, Bentley, Nicholas, Turner, Nigel, Cooney, Gregory J., Ruderman, Neil B., Kraegen, Edward W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370576/
https://ncbi.nlm.nih.gov/pubmed/25798922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121959
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