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Increasing Acyl CoA thioesterase activity alters phospholipid profile without effect on insulin action in skeletal muscle of rats

Increased lipid metabolism in muscle is associated with insulin resistance and therefore, many strategies have been employed to alter fatty acid metabolism and study the impact on insulin action. Metabolism of fatty acid requires activation to fatty acyl CoA by Acyl CoA synthases (ACSL) and fatty ac...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bakshi, Ishita, Brown, Simon H. J., Brandon, Amanda E., Suryana, Eurwin, Mitchell, Todd W., Turner, Nigel, Cooney, Gregory J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143561/
https://ncbi.nlm.nih.gov/pubmed/30228369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32354-w
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