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The HIP2~Ubiquitin Conjugate Forms a Non-Compact Monomeric Thioester during Di-Ubiquitin Synthesis

Polyubiquitination is a post-translational event used to control the degradation of damaged or unwanted proteins by modifying the target protein with a chain of ubiquitin molecules. One potential mechanism for the assembly of polyubiquitin chains involves the dimerization of an E2 conjugating enzyme...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Cook, Benjamin W., Barber, Kathryn R., Shilton, Brian H., Shaw, Gary S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370575/
https://ncbi.nlm.nih.gov/pubmed/25799589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120318
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