Mitochondrial-Targeted Antioxidant Therapy Decreases Transforming Growth Factor-β–Mediated Collagen Production in a Murine Asthma Model

Asthma is a disease of acute and chronic inflammation in which cytokines play a critical role in orchestrating the allergic inflammatory response. IL-13 and transforming growth factor (TGF)-β promote fibrotic airway remodeling, a major contributor to disease severity. Improved understanding is neede...

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Dettagli Bibliografici
Pubblicato in:Am J Respir Cell Mol Biol
Autori principali: Jaffer, Omar A., Carter, A. Brent, Sanders, Philip N., Dibbern, Megan E., Winters, Christopher J., Murthy, Shubha, Ryan, Alan J., Rokita, Adam G., Prasad, Anand M., Zabner, Joseph, Kline, Joel N., Grumbach, Isabella M., Anderson, Mark E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Thoracic Society 2015
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370251/
https://ncbi.nlm.nih.gov/pubmed/24988374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2013-0519OC
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