CaMKII inhibition in type II pneumocytes protects from bleomycin-induced pulmonary fibrosis by preventing Ca(2+)-dependent apoptosis

Por Winters, Christopher J., Koval, Olha, Murthy, Shubha, Allamargot, Chantal, Sebag, Sara C., Paschke, John D., Jaffer, Omar A., Carter, A. Brent, Grumbach, Isabella M.
Publicado no Am J Physiol Lung Cell Mol Physiol (2015)

Mitochondrial CaMKII inhibition in airway epithelium protects against allergic asthma

Por Sebag, Sara C., Koval, Olha M., Paschke, John D., Winters, Christopher J., Jaffer, Omar A., Dworski, Ryszard, Sutterwala, Fayyaz S., Anderson, Mark E., Grumbach, Isabella M.
Publicado no JCI Insight (2017)

Oxidative activation of the Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) regulates vascular smooth muscle migration and apoptosis

Por Zhu, Linda J., Klutho, Paula J., Scott, Jason A., Xie, Litao, Luczak, Elizabeth D., Dibbern, Megan E., Prasad, Anand M., Jaffer, Omar A., Venema, Ashlee N., Nguyen, Emily K., Guan, Xiaoqun, Anderson, Mark E., Grumbach, Isabella M.
Publicado em 2014

Mitochondrial-Targeted Antioxidant Therapy Decreases Transforming Growth Factor-β–Mediated Collagen Production in a Murine Asthma Model

Por Jaffer, Omar A., Carter, A. Brent, Sanders, Philip N., Dibbern, Megan E., Winters, Christopher J., Murthy, Shubha, Ryan, Alan J., Rokita, Adam G., Prasad, Anand M., Zabner, Joseph, Kline, Joel N., Grumbach, Isabella M., Anderson, Mark E.
Publicado no Am J Respir Cell Mol Biol (2015)

CaMKII Is Essential for the Proasthmatic Effects of Oxidation

Por Sanders, Philip N., Koval, Olha M., Jaffer, Omar A., Prasad, Anand M., Businga, Thomas R., Scott, Jason A., Hayden, Patrick J., Luczak, Elizabeth D., Dickey, David D., Allamargot, Chantal, Olivier, Alicia K., Meyerholz, David K., Robison, Alfred J., Winder, Danny G., Blackwell, Timothy S., Dworski, Ryszard, Sammut, David, Wagner, Brett A., Buettner, Garry R., Pope, Robert M., Miller, Francis J., Dibbern, Megan E., Haitchi, Hans Michael, Mohler, Peter J., Howarth, Peter H., Zabner, Joseph, Kline, Joel N., Grumbach, Isabella M., Anderson, Mark E.
Publicado no Sci Transl Med (2013)