NEDD9/Arf6-Dependent Endocytic Trafficking of Matrix Metalloproteinase 14: A Novel Mechanism for Blocking Mesenchymal Cell Invasion and Metastasis of Breast Cancer

NEDD9 is an established marker of invasive and metastatic cancers. NEDD9 downregulation has been shown to dramatically reduce cell invasion and metastasis in multiple tumors. The mechanisms by which NEDD9 regulates invasion are largely unknown. In the current study, we have found that NEDD9 is requi...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Loskutov, Yuriy V., Kozyulina, Polina Y., Kozyreva, Varvara K., Ice, Ryan J., Jones, Brandon C., Roston, Trevor J., Smolkin, Matthew B., Ivanov, Alexey V., Wysolmerski, Robert B., Pugacheva, Elena N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369482/
https://ncbi.nlm.nih.gov/pubmed/25241893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.297
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