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Dual Targeting of Mesenchymal and Amoeboid Motility Hinders Metastatic Behavior

Commonly upregulated in human cancers, the scaffolding protein NEDD9/HEF1 is a known regulator of mesenchymal migration and cancer cell plasticity. However, the functional role of NEDD9 as a regulator of different migration/invasion modes in the context of breast cancer metastasis is currently unkno...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Jones, Brandon C., Kelley, Laura C., Loskutov, Yuriy V., Marinak, Kristina M., Kozyreva, Varvara K., Smolkin, Matthew B., Pugacheva, Elena N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457705/
https://ncbi.nlm.nih.gov/pubmed/28235899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-16-0411
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