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Exogenous administration of thiosulfate, a donor of hydrogen sulfide, attenuates angiotensin II-induced hypertensive heart disease in rats

BACKGROUND AND PURPOSE: Hypertension is an important mediator of cardiac damage and remodelling. Hydrogen sulfide (H(2)S) is an endogenously produced gasotransmitter with cardioprotective properties. However, it is not yet in clinical use. We, therefore, investigated the protective effects of sodium...

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Bibliografske podrobnosti
izdano v:	Br J Pharmacol
Main Authors:	Snijder, P M, Frenay, A R, de Boer, R A, Pasch, A, Hillebrands, J L, Leuvenink, H G D, van Goor, H
Format:	Artigo
Jezik:	Inglês
Izdano:	BlackWell Publishing Ltd 2015
Teme:	Themed Section: Pharmacology of the Gasotransmitters
Online dostop:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4369259/ https://ncbi.nlm.nih.gov/pubmed/24962324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12825
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Exogenous administration of thiosulfate, a donor of hydrogen sulfide, attenuates angiotensin II-induced hypertensive heart disease in rats

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