Exogenous administration of thiosulfate, a donor of hydrogen sulfide, attenuates angiotensin II-induced hypertensive heart disease in rats

BACKGROUND AND PURPOSE: Hypertension is an important mediator of cardiac damage and remodelling. Hydrogen sulfide (H(2)S) is an endogenously produced gasotransmitter with cardioprotective properties. However, it is not yet in clinical use. We, therefore, investigated the protective effects of sodium...

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Udgivet i:Br J Pharmacol
Main Authors: Snijder, P M, Frenay, A R, de Boer, R A, Pasch, A, Hillebrands, J L, Leuvenink, H G D, van Goor, H
Format: Artigo
Sprog:Inglês
Udgivet: BlackWell Publishing Ltd 2015
Fag:
Themed Section: Pharmacology of the Gasotransmitters
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369259/
https://ncbi.nlm.nih.gov/pubmed/24962324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12825
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