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Exogenous administration of thiosulfate, a donor of hydrogen sulfide, attenuates angiotensin II-induced hypertensive heart disease in rats

BACKGROUND AND PURPOSE: Hypertension is an important mediator of cardiac damage and remodelling. Hydrogen sulfide (H(2)S) is an endogenously produced gasotransmitter with cardioprotective properties. However, it is not yet in clinical use. We, therefore, investigated the protective effects of sodium...

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Publicado en:Br J Pharmacol
Main Authors: Snijder, P M, Frenay, A R, de Boer, R A, Pasch, A, Hillebrands, J L, Leuvenink, H G D, van Goor, H
Formato: Artigo
Idioma:Inglês
Publicado: BlackWell Publishing Ltd 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369259/
https://ncbi.nlm.nih.gov/pubmed/24962324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12825
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