Exogenous administration of thiosulfate, a donor of hydrogen sulfide, attenuates angiotensin II-induced hypertensive heart disease in rats

BACKGROUND AND PURPOSE: Hypertension is an important mediator of cardiac damage and remodelling. Hydrogen sulfide (H(2)S) is an endogenously produced gasotransmitter with cardioprotective properties. However, it is not yet in clinical use. We, therefore, investigated the protective effects of sodium...

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Bibliografiset tiedot
Julkaisussa:Br J Pharmacol
Päätekijät: Snijder, P M, Frenay, A R, de Boer, R A, Pasch, A, Hillebrands, J L, Leuvenink, H G D, van Goor, H
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BlackWell Publishing Ltd 2015
Aiheet:
Themed Section: Pharmacology of the Gasotransmitters
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369259/
https://ncbi.nlm.nih.gov/pubmed/24962324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12825
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