Exogenous administration of thiosulfate, a donor of hydrogen sulfide, attenuates angiotensin II-induced hypertensive heart disease in rats

BACKGROUND AND PURPOSE: Hypertension is an important mediator of cardiac damage and remodelling. Hydrogen sulfide (H(2)S) is an endogenously produced gasotransmitter with cardioprotective properties. However, it is not yet in clinical use. We, therefore, investigated the protective effects of sodium...

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Bibliographic Details
Published in:Br J Pharmacol
Main Authors: Snijder, P M, Frenay, A R, de Boer, R A, Pasch, A, Hillebrands, J L, Leuvenink, H G D, van Goor, H
Format: Artigo
Language:Inglês
Published: BlackWell Publishing Ltd 2015
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Themed Section: Pharmacology of the Gasotransmitters
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369259/
https://ncbi.nlm.nih.gov/pubmed/24962324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12825
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