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DREADD: A Chemogenetic GPCR Signaling Platform

Recently, we created a family of engineered G protein-coupled receptors (GPCRs) called DREADD (designer receptors exclusively activated by designer drugs) which can precisely control three major GPCR signaling pathways (Gq, Gi, and Gs). DREADD technology has been successfully applied in a variety of...

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Bibliografische gegevens
Gepubliceerd in:Int J Neuropsychopharmacol
Hoofdauteurs: Zhu, Hu, Roth, Bryan L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368861/
https://ncbi.nlm.nih.gov/pubmed/25522378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyu007
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