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DREADD: A Chemogenetic GPCR Signaling Platform

Recently, we created a family of engineered G protein-coupled receptors (GPCRs) called DREADD (designer receptors exclusively activated by designer drugs) which can precisely control three major GPCR signaling pathways (Gq, Gi, and Gs). DREADD technology has been successfully applied in a variety of...

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Foilsithe in:Int J Neuropsychopharmacol
Main Authors: Zhu, Hu, Roth, Bryan L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368861/
https://ncbi.nlm.nih.gov/pubmed/25522378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyu007
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