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DREADD: A Chemogenetic GPCR Signaling Platform
Recently, we created a family of engineered G protein-coupled receptors (GPCRs) called DREADD (designer receptors exclusively activated by designer drugs) which can precisely control three major GPCR signaling pathways (Gq, Gi, and Gs). DREADD technology has been successfully applied in a variety of...
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Udgivet i: | Int J Neuropsychopharmacol |
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Main Authors: | , |
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Oxford University Press
2014
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4368861/ https://ncbi.nlm.nih.gov/pubmed/25522378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyu007 |
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