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DREADD: A Chemogenetic GPCR Signaling Platform

Recently, we created a family of engineered G protein-coupled receptors (GPCRs) called DREADD (designer receptors exclusively activated by designer drugs) which can precisely control three major GPCR signaling pathways (Gq, Gi, and Gs). DREADD technology has been successfully applied in a variety of...

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Bibliografiske detaljer
Udgivet i:Int J Neuropsychopharmacol
Main Authors: Zhu, Hu, Roth, Bryan L.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368861/
https://ncbi.nlm.nih.gov/pubmed/25522378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyu007
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