Melting Curve Analysis after T Allele Enrichment (MelcaTle) as a Highly Sensitive and Reliable Method for Detecting the JAK2V617F Mutation

Detection of the JAK2V617F mutation is essential for diagnosing patients with classical myeloproliferative neoplasms (MPNs). However, detection of the low-frequency JAK2V617F mutation is a challenging task due to the necessity of discriminating between true-positive and false-positive results. Here,...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Morishita, Soji, Takahashi, Kochi, Araki, Marito, Hironaka, Yumi, Sunami, Yoshitaka, Edahiro, Yoko, Tsutsui, Miyuki, Ohsaka, Akimichi, Tsuneda, Satoshi, Komatsu, Norio
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368779/
https://ncbi.nlm.nih.gov/pubmed/25794279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122003
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