Identification of AIM2 as a downstream target of JAK2V617F

BACKGROUND: The gain-of-function mutation JAK2V617F is frequently found in Philadelphia-chromosome-negative myeloproliferative neoplasm (MPN) patients. However, the tumorigenic properties of JAK2V617F have mostly been characterized in in vivo and in vitro murine models due to the lack of appropriate...

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Detalhes bibliográficos
Publicado no:Exp Hematol Oncol
Main Authors: Liew, Ei Leen, Araki, Marito, Hironaka, Yumi, Mori, Seiichi, Tan, Tuan Zea, Morishita, Soji, Edahiro, Yoko, Ohsaka, Akimichi, Komatsu, Norio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4730608/
https://ncbi.nlm.nih.gov/pubmed/26823993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-016-0032-7
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