Inhibition of the NAD-Dependent Protein Deacetylase SIRT2 Induces Granulocytic Differentiation in Human Leukemia Cells

Sirtuins, NAD-dependent protein deacetylases, play important roles in cellular functions such as metabolism and differentiation. Whether sirtuins function in tumorigenesis is still controversial, but sirtuins are aberrantly expressed in tumors, which may keep cancerous cells undifferentiated. Theref...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Sunami, Yoshitaka, Araki, Marito, Hironaka, Yumi, Morishita, Soji, Kobayashi, Masaki, Liew, Ei Leen, Edahiro, Yoko, Tsutsui, Miyuki, Ohsaka, Akimichi, Komatsu, Norio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584049/
https://ncbi.nlm.nih.gov/pubmed/23460888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057633
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados