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Detection of MPLW515L/K Mutations and Determination of Allele Frequencies with a Single-Tube PCR Assay
A gain-of-function mutation in the myeloproliferative leukemia virus (MPL) gene, which encodes the thrombopoietin receptor, has been identified in patients with essential thrombocythemia and primary myelofibrosis, subgroups of classic myeloproliferative neoplasms (MPNs). The presence of MPL gene mut...
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Main Authors: | , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4140728/ https://ncbi.nlm.nih.gov/pubmed/25144224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104958 |
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