Detection of MPLW515L/K Mutations and Determination of Allele Frequencies with a Single-Tube PCR Assay

A gain-of-function mutation in the myeloproliferative leukemia virus (MPL) gene, which encodes the thrombopoietin receptor, has been identified in patients with essential thrombocythemia and primary myelofibrosis, subgroups of classic myeloproliferative neoplasms (MPNs). The presence of MPL gene mut...

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Main Authors: Takei, Hiraku, Morishita, Soji, Araki, Marito, Edahiro, Yoko, Sunami, Yoshitaka, Hironaka, Yumi, Noda, Naohiro, Sekiguchi, Yuji, Tsuneda, Satoshi, Ohsaka, Akimichi, Komatsu, Norio
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2014
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140728/
https://ncbi.nlm.nih.gov/pubmed/25144224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104958
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