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Protein Domain-Level Landscape of Cancer-Type-Specific Somatic Mutations

Identifying driver mutations and their functional consequences is critical to our understanding of cancer. Towards this goal, and because domains are the functional units of a protein, we explored the protein domain-level landscape of cancer-type-specific somatic mutations. Specifically, we systemat...

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Publicat a:PLoS Comput Biol
Autors principals: Yang, Fan, Petsalaki, Evangelia, Rolland, Thomas, Hill, David E., Vidal, Marc, Roth, Frederick P.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368709/
https://ncbi.nlm.nih.gov/pubmed/25794154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004147
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