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Cancerouspdomains: comprehensive analysis of cancer type-specific recurrent somatic mutations in proteins and domains

BACKGROUND: Discriminating driver mutations from the ones that play no role in cancer is a severe bottleneck in elucidating molecular mechanisms underlying cancer development. Since protein domains are representatives of functional regions within proteins, mutations on them may disturb the protein f...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Hashemi, Seirana, Nowzari Dalini, Abbas, Jalali, Adrin, Banaei-Moghaddam, Ali Mohammad, Razaghi-Moghadam, Zahra
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559820/
https://ncbi.nlm.nih.gov/pubmed/28814324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1779-5
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