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Salt Potentiates Methylamine Counteraction System to Offset the Deleterious Effects of Urea on Protein Stability and Function

Cellular methylamines are osmolytes (low molecular weight organic compounds) believed to offset the urea’s harmful effects on the stability and function of proteins in mammalian kidney and marine invertebrates. Although urea and methylamines are found at 2:1 molar ratio in tissues, their opposing ef...

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Publicado en:PLoS One
Autores principales: Rahman, Safikur, Rehman, Md. Tabish, Singh, Laishram R., Warepam, Marina, Ahmad, Faizan, Dar, Tanveer Ali
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368626/
https://ncbi.nlm.nih.gov/pubmed/25793733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119597
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