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Salt Potentiates Methylamine Counteraction System to Offset the Deleterious Effects of Urea on Protein Stability and Function

Cellular methylamines are osmolytes (low molecular weight organic compounds) believed to offset the urea’s harmful effects on the stability and function of proteins in mammalian kidney and marine invertebrates. Although urea and methylamines are found at 2:1 molar ratio in tissues, their opposing ef...

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Bibliographic Details
Published in:PLoS One
Main Authors: Rahman, Safikur, Rehman, Md. Tabish, Singh, Laishram R., Warepam, Marina, Ahmad, Faizan, Dar, Tanveer Ali
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368626/
https://ncbi.nlm.nih.gov/pubmed/25793733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119597
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