Testing the Ability of Non-Methylamine Osmolytes Present in Kidney Cells to Counteract the Deleterious Effects of Urea on Structure, Stability and Function of Proteins

Human kidney cells are under constant urea stress due to its urine concentrating mechanism. It is believed that the deleterious effect of urea is counteracted by methylamine osmolytes (glycine betaine and glycerophosphocholine) present in kidney cells. A question arises: Do the stabilizing osmolytes...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Khan, Sheeza, Bano, Zehra, Singh, Laishram R., Hassan, Md. Imtaiyaz, Islam, Asimul, Ahmad, Faizan
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science 2013
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767660/
https://ncbi.nlm.nih.gov/pubmed/24039776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072533
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