Time-Dependent Effect of Hypoxia on Tumor Progression and Liver Progenitor Cell Markers in Primary Liver Tumors

BACKGROUND & AIMS: Expression of liver progenitor cell (LPC) characteristics has been proposed as a negative prognostic marker in primary liver tumors. Hypoxia has been linked to activation of the Notch pathway which is responsible for activation and proliferation of LPCs and hypoxia-induced LPC...

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Veröffentlicht in:PLoS One
Hauptverfasser: Bogaerts, Eliene, Heindryckx, Femke, Devisscher, Lindsey, Paridaens, Annelies, Vandewynckel, Yves-Paul, Van den Bussche, Anja, Verhelst, Xavier, Libbrecht, Louis, van Grunsven, Leo A., Geerts, Anja, Van Vlierberghe, Hans
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368520/
https://ncbi.nlm.nih.gov/pubmed/25793288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119555
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