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Regulatory T cells in B-cell-deficient and wild-type mice differ functionally and in expression of cell surface markers

NOD.H-2h4 mice develop spontaneous autoimmune thyroiditis (SAT) with chronic inflammation of thyroids by T and B cells. B-cell deficient (B(–/–)) mice are resistant to SAT but develop SAT if regulatory T (Treg) cells are transiently depleted. We established a transfer model using splenocytes from CD...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Ellis, Jason S, Braley-Mullen, Helen
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368166/
https://ncbi.nlm.nih.gov/pubmed/25318356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12410
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