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B cell–deficient NOD.H-2h4 mice have CD4(+)CD25(+) T regulatory cells that inhibit the development of spontaneous autoimmune thyroiditis

Wild-type (WT) NOD.H-2h4 mice develop spontaneous autoimmune thyroiditis (SAT) when given 0.05% NaI in their drinking water, whereas B cell–deficient NOD.H-2h4 mice are SAT resistant. To test the hypothesis that resistance of B cell–deficient mice to SAT was due to the activity of regulatory CD4(+)C...

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Detalhes bibliográficos
Main Authors: Yu, Shiguang, Maiti, Prasanta K., Dyson, Melissa, Jain, Renu, Braley-Mullen, Helen
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118195/
https://ncbi.nlm.nih.gov/pubmed/16446379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051438
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