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Transient depletion of CD4(+) CD25(+) regulatory T cells results in multiple autoimmune diseases in wild-type and B-cell-deficient NOD mice
Approximately 80% of female wild-type non-obese diabetic (WT NOD) mice spontaneously develop diabetes, whereas B-cell-deficient (B(−/−)) NOD mice are resistant to diabetes. B(−/−) mice are also resistant to other spontaneous and experimentally induced autoimmune diseases, including arthritis, system...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3647184/ https://ncbi.nlm.nih.gov/pubmed/23293979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12065 |
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