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MicroRNA silencing for cancer therapy targeted to the tumor microenvironment

MicroRNAs (miRNAs) are short non-coding RNAs expressed in different tissue and cell types that suppress the expression of target genes. As such, miRNAs are critical cogs in numerous biological processes(1,2), and dysregulated miRNA expression is correlated with many human diseases. Certain miRNAs, c...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Cheng, Christopher J., Bahal, Raman, Babar, Imran A., Pincus, Zachary, Barrera, Francisco, Liu, Connie, Svoronos, Alexander, Braddock, Demetrios T., Glazer, Peter M., Engelman, Donald M., Saltzman, W. Mark, Slack, Frank J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367962/
https://ncbi.nlm.nih.gov/pubmed/25409146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13905
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