Novel genetic matching methods for handling population stratification in genome-wide association studies

BACKGROUND: A usually confronted problem in association studies is the occurrence of population stratification. In this work, we propose a novel framework to consider population matchings in the contexts of genome-wide and sequencing association studies. We employ pairwise and groupwise optimal case...

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Опубликовано в: :BMC Bioinformatics
Главные авторы: Lacour, André, Schüller, Vitalia, Drichel, Dmitriy, Herold, Christine, Jessen, Frank, Leber, Markus, Maier, Wolfgang, Noethen, Markus M, Ramirez, Alfredo, Vaitsiakhovich, Tatsiana, Becker, Tim
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2015
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367953/
https://ncbi.nlm.nih.gov/pubmed/25880419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0521-4
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