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Joint analysis of tightly linked SNPs in screening step of genome-wide association studies leads to increased power

Recent developments in genome-wide association studies (GWAS) have lead to the localization of disease genes for many complex diseases. The scrutiny of the respective publications reveals, first, that statistical analysis is restricted typically to single-marker analysis in the first step, and that,...

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Detalhes bibliográficos
Main Authors: Becker, Tim, Herold, Christine
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2986547/
https://ncbi.nlm.nih.gov/pubmed/19223937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2009.7
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