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Multi-locus Test Conditional on Confirmed Effects Leads to Increased Power in Genome-wide Association Studies
Complex diseases or phenotypes may involve multiple genetic variants and interactions between genetic, environmental and other factors. Current genome-wide association studies (GWAS) mostly used single-locus analysis and had identified genetic effects with multiple confirmations. Such confirmed sing...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2982824/ https://ncbi.nlm.nih.gov/pubmed/21103364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015006 |
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