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Statistical power in genome-wide association studies and quantitative trait locus mapping

Power calculation prior to a genetic experiment can help investigators choose the optimal sample size to detect a quantitative trait locus (QTL). Without the guidance of power analysis, an experiment may be underpowered or overpowered. Either way will result in wasted resource. QTL mapping and genom...

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Détails bibliographiques
Publié dans:Heredity (Edinb)
Auteurs principaux: Wang, Meiyue, Xu, Shizhong
Format: Artigo
Langue:Inglês
Publié: Springer International Publishing 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781134/
https://ncbi.nlm.nih.gov/pubmed/30858595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41437-019-0205-3
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