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Multi-locus Test Conditional on Confirmed Effects Leads to Increased Power in Genome-wide Association Studies

Complex diseases or phenotypes may involve multiple genetic variants and interactions between genetic, environmental and other factors. Current genome-wide association studies (GWAS) mostly used single-locus analysis and had identified genetic effects with multiple confirmations. Such confirmed sing...

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Main Authors: Ma, Li, Han, Shizhong, Yang, Jing, Da, Yang
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2982824/
https://ncbi.nlm.nih.gov/pubmed/21103364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015006
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