Quick, “Imputation-free” meta-analysis with proxy-SNPs

BACKGROUND: Meta-analysis (MA) is widely used to pool genome-wide association studies (GWASes) in order to a) increase the power to detect strong or weak genotype effects or b) as a result verification method. As a consequence of differing SNP panels among genotyping chips, imputation is the method...

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Bibliografiske detaljer
Main Authors: Meesters, Christian, Leber, Markus, Herold, Christine, Angisch, Marina, Mattheisen, Manuel, Drichel, Dmitriy, Lacour, André, Becker, Tim
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Methodology Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472171/
https://ncbi.nlm.nih.gov/pubmed/22971100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-231
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