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Comparisons with Amyloid-β Reveal an Aspartate Residue That Stabilizes Fibrils of the Aortic Amyloid Peptide Medin

Aortic medial amyloid (AMA) is the most common localized human amyloid, occurring in virtually all of the Caucasian population over the age of 50. The main protein component of AMA, medin, readily assembles into amyloid-like fibrils in vitro. Despite the prevalence of AMA, little is known about the...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Davies, Hannah A., Madine, Jillian, Middleton, David A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367279/
https://ncbi.nlm.nih.gov/pubmed/25614623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.602177
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