BRICHOS Domains Efficiently Delay Fibrillation of Amyloid β-Peptide

Amyloid diseases such as Alzheimer, Parkinson, and prion diseases are associated with a specific form of protein misfolding and aggregation into oligomers and fibrils rich in β-sheet structure. The BRICHOS domain consisting of ∼100 residues is found in membrane proteins associated with degenerative...

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Detalhes bibliográficos
Main Authors: Willander, Hanna, Presto, Jenny, Askarieh, Glareh, Biverstål, Henrik, Frohm, Birgitta, Knight, Stefan D., Johansson, Jan, Linse, Sara
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438992/
https://ncbi.nlm.nih.gov/pubmed/22801430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.393157
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