ATM has a major role in the double-strand break repair pathway dysregulation in sporadic breast carcinomas and is an independent prognostic marker at both mRNA and protein levels

BACKGROUND: Ataxia telangiectasia mutated (ATM) is a kinase that has a central role in the maintenance of genomic integrity by activating cell cycle checkpoints and promoting repair of DNA double-strand breaks (DSB). In breast cancer, a low level of ATM was correlated with poor outcome; however, the...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Br J Cancer
Main Authors: Rondeau, S, Vacher, S, De Koning, L, Briaux, A, Schnitzler, A, Chemlali, W, Callens, C, Lidereau, R, Bièche, I
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2015
נושאים:
Molecular Diagnostics
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366900/
https://ncbi.nlm.nih.gov/pubmed/25742469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.60
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים