Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development

Brown adipose tissue (BAT) combusts high amounts of fatty acids, thereby lowering plasma triglyceride levels and reducing obesity. However, the precise role of BAT in plasma cholesterol metabolism and atherosclerosis development remains unclear. Here we show that BAT activation by β3-adrenergic rece...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Berbée, Jimmy F. P., Boon, Mariëtte R, Khedoe, P. Padmini S. J., Bartelt, Alexander, Schlein, Christian, Worthmann, Anna, Kooijman, Sander, Hoeke, Geerte, Mol, Isabel M., John, Clara, Jung, Caroline, Vazirpanah, Nadia, Brouwers, Linda P.J., Gordts, Philip L.S.M., Esko, Jeffrey D., Hiemstra, Pieter S., Havekes, Louis M., Scheja, Ludger, Heeren, Joerg, Rensen, Patrick C.N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Pub. Group 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366535/
https://ncbi.nlm.nih.gov/pubmed/25754609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7356
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