The Effects of Selective Hematopoietic Expression of Human IL-37 on Systemic Inflammation and Atherosclerosis in LDLr-Deficient Mice

The human cytokine interleukin (IL)-37 has potent anti-inflammatory capacities, and hematopoietic cell-specific transgenic overexpression of IL-37 in mice protects against septic shock and colitis. In the present study we investigated the effect of hematopoietic expression of IL-37 on atherosclerosi...

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Udgivet i:Int J Mol Sci
Main Authors: Hoeke, Geerte, Khedoe, P. Padmini S.J., van Diepen, Janna A., Pike-Overzet, Karin, van de Ven, Britt, Vazirpanah, Nadia, Mol, Isabel, Hiemstra, Pieter S., Staal, Frank J.T., Stienstra, Rinke, Netea, Mihai G., Dinarello, Charles A., Rensen, Patrick C.N., Berbée, Jimmy F.P.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578062/
https://ncbi.nlm.nih.gov/pubmed/28792474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18081672
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